課程資訊
課程名稱
 醫用超音波學
Biomedical Ultrasonics 
開課學期
 100-1 
授課對象
 工學院  醫學工程學研究所  
授課教師
 林文澧 
課號
 Biomed7047 
課程識別碼
 548 M0820 
班次
  
學分
 3 
全/半年
 半年 
必/選修
 選修 
上課時間
 星期四6,7,8(13:20~16:20) 
上課地點
  
備註
 本課程中文授課,使用英文教科書。教室：基醫505
總人數上限：30人 
Ceiba 課程網頁
 http://ceiba.ntu.edu.tw/1001BU_Lin 
課程簡介影片
 
核心能力關聯
 核心能力與課程規劃關聯圖
課程大綱
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課程概述

1. Physics of Medical Ultrasound
a. Ultrasound field; Nonlinear effects in ultrasound propagation
b. Radiation pressure and acoustic streaming; Ultrasound properties of tissues
2. Technology and Measurement in Diagnostic Imaging
a. Transducer arrays for medical ultrasound imaging
b. Current Doppler technology and techniques
c. The purpose and techniques of acoustic output measurement
3. Ultrasound Hyperthermia and Surgery
a. Ultrasound hyperthermia and the prediction of heating
b. Focused ultrasound surgery
4. Acoustic wave lithotripsy
5. Ultrasound and Bubbles
a. Acoustic cavitation; Echo-enhancing agents; Sonochemistry and drug delivery
6. Research Topics in Medical Ultrasound
a. Imaging elastic properties of tissue
b. Signal-to-noise relationship for investigative ultrasound
c. Challenges in ultrasonic measurement of bone
7. Acoustic Wave Sensors and Responses
a. Thickness-shear mode (TSM) resonator; Surface acoustic wave devices
8. Chemical and Biological Sensors
a. Detection mechanism; Performance criteria
b. Coating-analyte interactions and acoustic-wave chemical sensors
c. Sensor arrays and pattern recognition
持續改善：因應本屆修課學生的程度，調整課程教學的速度及深淺，加入期中考評分以促進上課及學習氣氛。 

課程目標
 使學生熟悉超音波原理，超波音診斷、治療系統的架構及其在醫療上的應用。 
課程要求
 期末考、
期未報告：
一人交一份期未報告
於期未前兩週公佈相關題目
依題目要求尋找三至五篇相關paper
整理成一份書面報告及簡報檔
並於學期未上台做十五~二十分鐘的內容報告。 
預期每週課後學習時數
  
Office Hours
 另約時間 
指定閱讀
 無 
參考書目
 References:
1. Ultrasound in Medicine, Edited by Duck FA, Baker AC and Starritt HC,
Institute of Physics Publishing, 1998.
2. Acoustic wave sensors: theory, design, and physico-chemical applications,
Edited by Ballantine DS Jr, White RM, Martin SJ, Zellers ET, and Whohltjen H,
Academic Press, 1997
3. Jounral papers 
評量方式
(僅供參考)
  
No.
項目
百分比
說明
1. 
 Presentation and Report 
50% 
 Presentation (20min, 25%) and Report (about 8 pages, 25%) for high impact journal papers within three years. 
2. 
 Exam (closed book) 
50% 
  
 
課程進度
週次
日期
單元主題
第1週
 2011/09/15  1. Physics of Medical Ultrasounda. Ultrasound field; Nonlinear effects in ultrasound propagation b. Radiation pressure and acoustic streaming; Ultrasound properties of tissues [核心能力：2、4] 
第2週
 2011/09/22  1. Physics of Medical Ultrasound a. Ultrasound field; Nonlinear effects in ultrasound propagation b. Radiation pressure and acoustic streaming; Ultrasound properties of tissues [核心能力：2、4] 
第3週
 2011/09/29  2.Ultrasound properties of tissues and bioeffects [核心能力：2、4] 
第4週
 2011/10/06  2. Technology and Measurement in Diagnostic Imaginga. Transducer arrays for medical ultrasound imagingb. Current Doppler technology and techniques [核心能力：2、4] 
第5週
 2011/10/13  3.Technology and Measurement in Diagnostic ImagingTransducer arrays for medical ultrasound imaging; Current Doppler technology and techniques; Purpose and techniques of acoustic output measurement [核心能力：2、4] 
第6週
 2011/10/20  3.Technology and Measurement in Diagnostic ImagingTransducer arrays for medical ultrasound imaging; Current Doppler technology and techniques; Purpose and techniques of acoustic output measurement [核心能力：2、4] 
第7週
 2011/10/27  3.Technology and Measurement in Diagnostic ImagingTransducer arrays for medical ultrasound imaging; Current Doppler technology and techniques; Purpose and techniques of acoustic output measurement [核心能力：2、4] 
第8週
 2011/11/03  4.Ultrasound Thermal Therapy Ultrasound hyperthermia; Focused ultrasound surgery [核心能力：2、4] 
第9週
 2011/11/10  5.Acoustic wave lithotripsy [核心能力：2、4] 
第10週
 2011/11/17  6.Ultrasound and MicrobubblesUltrasound contrast agent; Acoustic cavitation; Sonochemistry, [核心能力：2、4] 
第11週
 2011/11/24  6.Ultrasound and Microbubbles Ultrasound contrast agent; Acoustic cavitation; Sonochemistry, [核心能力：2、4] 
第12週
 2011/12/01  7.Research Topics for Medical Ultrasound Imaging elastic properties of tissue; Blood-brain barrier disruption; Targeted drug and gene delivery; Image-guided focused ultrasound; Development of focused ultrasound system; Challenges in ultrasonic measurement of bone; Acoustic lense. [核心能力：2、4] 
第13週
 2011/12/08  Mid-term Exam 
第14週
 2011/12/15  7.Research Topics for Medical Ultrasound Imaging elastic properties of tissue; Blood-brain barrier disruption; Targeted drug and gene delivery; Image-guided focused ultrasound; Development of focused ultrasound system; Challenges in ultrasonic measurement of bone; Acoustic lense. [核心能力：2、4] 
第15週
 2011/12/22  7.Research Topics for Medical Ultrasound Imaging elastic properties of tissue; Blood-brain barrier disruption; Targeted drug and gene delivery; Image-guided focused ultrasound; Development of focused ultrasound system; Challenges in ultrasonic measurement of bone; Acoustic lense. [核心能力：2、4] 
第16週
 2011/12/29  Final report presentation [核心能力：2、4] 
第17週
 2012/01/05  Final report presentation [核心能力：2、4] 
第18週
 2012/01/12  Final report presentation
期末問卷填寫 [核心能力：2、4]